Published Research & Presentations

Published Research & Presentations

poster:
Engineering and Preclinical Activity of MM-201, a Potentially Best-in-Class TRAIL Receptor Agonist

Sawyer et al, AACR, 2019
poster:
Development of a second-generation TRAIL agonist and predictive biomarker profile for colorectal cancer

Ghassemifar et al, AACR, 2019
poster:
A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity

Sampson et al, AACR, 2019
poster:
MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memory

Richards et al, AACR, 2019
poster:
Mechanism of action of a novel agonist TNFR2-antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity

Fulton et al, AACR, 2019
poster:
MM-401: A novel antibody that targets TNFR2, a key regulator of the tumor immunosuppressive microenvironment

Raue et al., EORTC-NCI-AACR, 2018.
publication:
Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway

Alkan et al., Science Signaling, July 2018.
poster:
Understanding chemotherapy-induced replicative stress to identify rational combination therapies

Alkan et al., AACR, 2018.
poster:
Predicting ligand-dependent tumors from multi-dimensional signaling features

Hass et al., AACR, 2018.
poster:
Development of TNF superfamily agonists: 4-1BB ligand fusion shows anti-tumor activity in vivo

Tam et al., AACR, 2018.
publication:
Estimation of immune cell content in tumour tissue using single-cell RNA-seq data

Schelker et al., Nature Communications, 2017
poster:
MM-161, A First-In-Class Pan-FGFR Antibody

Dake et al., AACR, 2017.
poster:
Estimation of immune cell content in bulk tumour tissue using reference profiles from single-cell RNA-seq data

Schelker et al., AACR, 2017.